Walmart is set to replace AstraZeneca in the Nasdaq-100 Index, effective January 20, following the index's annual rebalancing. This move comes after Walmart shifted its stock listing from the New York Stock Exchange to Nasdaq. The Nasdaq-100 tracks 100 of the largest non-financial companies on the Nasdaq market. Walmart's inclusion highlights its growth in digital operations and AI integration, while AstraZeneca's exit follows a period of underperformance as focus shifted to obesity treatments.