Sixth-tier Macclesfield earned a home FA Cup fourth-round tie against Premier League side Brentford after a significant upset victory over Crystal Palace. This result marked one of the biggest FA Cup shocks, contributing to six top-flight teams being eliminated in the third round. Other notable draws include Chelsea facing Hull, Manchester City playing Salford City or Swindon, and Arsenal hosting Wigan. Aston Villa will host Newcastle in the sole guaranteed all-Premier League fixture.