A study published in General Psychiatry suggests that frailty and depression in older adults, when combined, may account for 17% of dementia risk. Researchers analyzed data from over 200,000 individuals in the US and UK over 13 years. While frailty alone increased dementia risk by 2.5 times and depression by 60%, having both conditions significantly elevated the risk, making individuals more than three times as likely to develop dementia compared to healthy peers. The study recommends routine assessment of frailty and depression in older populations.