Amanda Nguyen, a civil rights activist and member of Blue Origin's first all-female crew since 1963, revealed she experienced severe depression and harassment following her April 2025 spaceflight. The NS-31 mission, which included other notable figures, faced public criticism for its environmental impact and perceived exclusivity. Nguyen described the backlash as an "avalanche of misogyny" that significantly affected her mental health, leading to a week of incapacitation.